CD274 and neoplasm: There was an association between CD68/PD-L1 double-positive and negative samples and high and low CD8/PD-L1 double-positive cell count (p = 0.008) and the median cell count of CD8/PD-L1 double-positive cells was significantly higher in the CD68/PD-L1 double-positive tumours than in the negative tumours (p = 0.000) (Fig. 2b).