CDX1 and colorectal carcinoma: To gain insight into how re-expression of EHF and CDX1 promotes differentiation of CRC cells, we performed parallel RNA-seq and ATAC-seq analysis on HCT116EV, HCT116EHF, HCT116CDX1 and HCT116EHF + CDX1 cells to assess global transcriptomic changes and associated chromatin remodelling events.