GSK3B and glioblastoma: We identified palmitoylation of GSK3β using ABE and found that both the GSK3β mutant (cysteine 14 mutated to alanine) and the siRNA silencing of ZDHHC4 made GSK3β palmitoylation significantly reduced in SF126 GBM cells, similar to the U118MG cell line (Fig. 1E; Supplementary Fig. 1B, C).