LPA and coronary artery disorder: For example, Zeng et al. found that the effect of rs140570886 on Lp(a) and CAD depends on the haplotype of rs1800769 (promoter) and rs9458001 (enhancer), while, vice versa, only the minor allele of rs140570886 enables a strong effect of rs1800769 on Lp(a) [104].