A recent study suggested that HF is induced or aggravated via inflammation provoked by somatic mutations associated with clonal haematopoiesis of indeterminate potential (CHIP), such as tet methylcytosine dioxygenase 2 (TET2) and deoxyribonucleic acid methyltransferase 3 alpha (DNMT3A).29 Patients with a CHIP mutation had a low survival rate, possibly due to anthracycline resistance30; therefore, the possibility that CHIP acts as a common background for cardiac dysfunction after HSCT and the refractoriness of haematological malignancies should be investigated in future studies. The gene discussed is TET2; the disease is hydrops fetalis.