IGF1 and polycystic ovary syndrome: Although compared to the PCOS group, treatment with 400 mg/kg of RD extract was ineffective in improving some parameters, including reducing ovary weight, serum TC, HDL, ALP, LH, IGF-1 gene expression, and increasing PFs and CLs, higher doses of RD extract, including 800 and 1200 mg/kg, were found to significantly improve the status of all parameters.