IGF1 and polycystic ovary syndrome: In the present study, we investigated the potential therapeutic effects of a standardized extract of RD based on quercetin and gallic acid on a rat model of PCOS induced by EV via investigating body and ovarian weight, ovarian histology in terms of the number of follicles and follicular growth cycle, glycemic parameters, serum lipid profile, liver enzymes, sex hormone levels, and IGF-1 expression.