LIGHT-deficient mice displayed strongly reduced epidermal thickening, with reduced collagen deposition in the dermis, in models of bleomycin-induced scleroderma and allergen-induced atopic dermatitis, along with lower expression of other markers of skin inflammation (Herro et al., 2015; Herro et al., 2018). Here, TNFSF14 is linked to scleroderma.