To further assess the role of the CXCL10/CXCR3 axis in disease pathogenesis upon CVA2 infection, 5-day-old mice were injected intraperitoneally (i.p.)with CVA2 and then treated with isotype IgG or αCXCR3 (Fig. 4A). The gene discussed is CXCR3; the disease is infection.