This function of FcRn could have important implications during echovirus infections: FcRn could (i) mediate the internalization of viral particles into intracellular compartments that facilitate uncoating and subsequent replication and/or (ii) mediate the direct transcytosis of viral particles across the intestinal epithelium from the lumen into underlying tissue. The gene discussed is FCGRT; the disease is Echovirus infectious disease.