Consistent with this logic, our studies found that the silencing of DDX5 using DDX5‐specific shRNA (Figure S5) either in PDAC cells or in CRC cells resulted in decreased expression of survivin, Mcl‐1, XIAP, cIAP2 and c‐Myc (a known DDX5 target; Figure 3A,B, left panels). This evidence concerns the gene BIRC5 and colorectal carcinoma.