PPARD and cancer: Cancer cells rely on FAO for proliferation, survival, stemness, drug resistance, and metastatic progression.[36] It was reported that PPARδ drives the expression of various FAO enzymes to promote FAO in hematopoietic stem cells.[37] Another study reported that CD36‐positive leukemic stem cells displayed a higher FAO rate and more resistance to drugs than CD36‐negative counterparts, indicating that FAO activity was a determinant of cancer stem cell properties.