Thus, when many neutrophils arriving at the site of infection or inflammation, they create a low pH microenvironment during phagocytosis, degranulation or association with neutrophil extracellular traps (NETs).[43, 44] Taking advantage of this characteristic, the pH‐responsive hydrogel dissociated, and SiO2‐FasL was released to induce apoptosis in activated neutrophils. Here, FASLG is linked to infection.