ANPEP and early-onset autosomal dominant Alzheimer disease: In previous studies, our research methods have been widely used, such as the screening of CD13 natural inhibitors [46], bacopa monnieri in the treatment of Alzheimer’s Disease [47], novel inhibitors against β-lactamase CTX-m-152 [48], MCL-1 inhibitors [49], etc., using the same or similar research methods as ours.