The KEGG pathway analysis revealed that the up-regulated DEGs were significantly enriched in cytokine-cytokine receptor interaction (map04060), TNF signaling pathway (map04668) and vascular smooth muscle contraction (map04270) (Figure 4(d)), while the down-regulated DEGs were significantly enriched in prostate cancer (map05215), Ras signaling pathway (map04014) and microRNAs in cancer (map05206) (Figure 4(e)). The gene discussed is TNF; the disease is prostate cancer.