SERPINE1 and acute myeloblastic leukemia with maturation: Last but not least, the biological functions of several DEGs, including HOXC8, TCF21, CACNG7, FOXC2, SERPINE1, ADGRA2, NTF3, TLR3, GATA6, KCTD8 and DTX1 in the pathophysiology of AM remained unclear and should be further explored by in vitro and in vivo studies.