In the subgroup analysis of IL‐6, heterogeneity was reduced in the subgroups of the missing BMI group (I2 = 0.0%, P = 0.736), studies that examined the plasma samples (I2 = 40.5%, P = 0.151) and diagnosing NAFLD by ultrasonography examination (I2 = 44.5%, P = 0.180). Here, IL6 is linked to metabolic dysfunction-associated steatotic liver disease.