We also revealed injured and repair associated genes and transcription factors such as Hif (32), Irf1 (33), Klf4 (25), Hes1 (34), and Klf6 (26) (Figures 4D, E) involved in AKI progression, which may be important biomarkers for screening AKI progression. The gene discussed is KLF6; the disease is acute kidney injury.