TLR5 and systemic lupus erythematosus: We observed that the single measurement of SLEB1 and SLESMB better discriminates SLE from autoimmune controls compared to SLEcTFH (SLEB1/SLESMB AUC = 0.81 vs. SLEcTFH AUC = 0.72, Figure 6B and Supplementary Figure 8).