Nevertheless, achieving a specific diagnosis is often challenging owing to the significant degree of morphological and immunophenotypic overlap between the benign and malignant lesions such as polymorphous B-cell LP is a masquerader of Hodgkin lymphoma (HL) and benign CD8+T-cell/histiocytic infiltrates in common variable immunodeficiency (CVID) could be easily confused with mimicking T- large granular lymphocytic leukemia (T-LGLL) leading to overtreatment. Here, CD8A is linked to common variable immunodeficiency.