Thus, CAR-γδ T cells have been designed to target many solid tumor antigens, such as disialoganglioside 2 (GD2) on neuroblastoma and Ewing sarcoma (136), melanoma chondroitin sulfate proteoglycan (MCSP) on melanoma lesions (137), original or glycosylated Mucin 1 (MUC1) on breast cancer, head and neck squamous cell carcinoma (138, 139). This evidence concerns the gene MUC1 and breast carcinoma.