For example, transferring αβ TCRs derived from invariant natural killer T (iNKT) cells, which recognized glycolipid antigens presented by CD1d, the TCR-γδ T cells were found to respond to CD1d via both endogenous γδ TCRs and transferred αβ TCRs, and had increasing antitumor effect against the CD1d positive leukemia cell line K562 (143). This evidence concerns the gene CD1D and leukemia.