CCL2 and systemic sclerosis: al., compared the serum of UCTD-risk-SSc patients to fibromyalgia and/or osteoarthritis controls without RP, and definite SSc patients for soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular adhesion molecule-1 (sVCAM-1), CCL2, CXCL8, IL-13, IL-33, and transforming growth factor-β (TGF-β) (17).