And The Kaplan-Meier survival analysis showed the DM-ILD patients with negative MSA/MAA patients had the most favorable prognosis while MDA5+ DM+ILD had the worst prognosis, All of which indicating that DM-ILD patients with negative MSA/MAA had a favorable prognosis, although some patients may develop RP-ILD. This evidence concerns the gene IFIH1 and interstitial lung disease.