Our study was the first to suggest that TFR1 expression has a significantly positive correlation with the levels of Th1/Th17-related inflammatory cytokines (IL-1β, TNF-α, IL-6, IFN-γ, and IL-17A) in induced sputum, indicating that increasing TFR1 expression in induced sputum is related to inflammatory responses in asthma development. Here, TNF is linked to asthma.