In addition, the enriched KEGG pathway was found to be involved in Hepatitis B (hsa05161)- and tumour (hsa05200, hsa05230, hsa05206, hsa05205)-related pathways, and BCR, RB1, PDGFRB, RET, CASP8, APC, LAMA2, CDH1, ERBB2, CBL, FGFR3, and TP53 played a key role in carcinogenesis and tumour progression. This evidence concerns the gene CASP8 and neoplasm.