Common features included proteinuria (1.6–10 g/d), normal lecithin-cholesterol acyltransferase (LCAT) activity, type III HLP-like lipoprotein profiles, and significantly higher levels of plasma apoE (>10 mg/dL) compared with the control patients with hyperlipidemic nephrotic syndrome without lipoprotein thrombi, or type IIb hyperlipoproteinemia without renal disease. Here, LCAT is linked to nephrotic syndrome.