On the foundation of its low sequencing homology with Nip3 and structure similarity with Bcl-2 family protein, as a mitochondrial antiapoptotic protein, HAX-1 is considered to participate in apoptotic events or programmed CD regulation, and its abnormal expression is related to many serious diseases, including neurodevelopmental delay, cancer, and cardiovascular disease [20, 21]. The gene discussed is HAX1; the disease is cancer.