TIGIT and neoplasm: For grasping the landscape of the tumor immune microenvironment (TME) of TNBC, we firstly compared the expressions of the immune checkpoint molecules between the high-CNI and low-CNI groups, and the result indicated that most of them are highly expressed in the low-CNI group, including CD247, CTLA4, IDO1, LAG3, PDCD1, TIGIT, CD96, and IFNG (Figure 9A, Supplementary Figure S1).