In addition, we have recently shown an immunomodulatory effect of this peptide, which significantly decreased the expression of IL-1β in tumor and lung tissues and increased the levels of IL-10 anti-inflammatory cytokines in the primary tumor of 4T1 mouse mammary carcinoma (Abdel Salam et al., 2021) as observed in other AMPs. Here, IL1B is linked to breast carcinoma.