It has also been reported that deletion of the protocadherin FAT1 induces a hybrid EMT state in skin squamous cell carcinoma and lung tumors by triggering not only CAMK2–CD44–SRC axis‐mediated YAP1 activation and ZEB1 expression but also EZH2‐regulated SOX2 expression, thus resulting in maximal stemness and accelerated cancer progression.114. The gene discussed is CD44; the disease is cancer.