HDAC1 and familial pancreatic carcinoma: For example, Snail has been found to form protein complex with HDAC1 and HDAC2 at the promoter of E‐cadherin, leading to the deacetylation and consequent repression of E‐cadherin, which results in the EMT and migration of breast cancer, pancreatic cancer, and nasopharyngeal cancer.233, 234, 235, 236