Recent studies have shown that SHC1 is associated with several clinical diseases, especially in tumor development and progression (Falco et al., 2005; Smith et al., 2006; Ahn et al., 2017b; Chao et al., 2019b; Huang et al., 2019; Wright et al., 2019; Borah and Bhowmick, 2020; Kiepas et al., 2020). Here, SHC1 is linked to neoplasm.