Hsa-miR-129-5p, a tumor suppressor, is down-regulated in gliomas and inhibits glioma proliferation, migration and development by targeting TGIF2, WNT5A, DNMT3A, HOXC10, FNDC3B (Xu et al., 2017; Gu et al., 2018; Zeng et al., 2018; Liu et al., 2020a). The gene discussed is DNMT3A; the disease is central nervous system cancer.