FOXP3 and diffuse large B-cell lymphoma: Studies have shown that high infiltration of FOXP3+ Tregs cells in DLBCL is associated with better prognosis, but these studies have targeted the entire FOXP3 population rather than the true Tregs cells (eTregs) that are essential for the impact of tumor immunity (Lee et al., 2008; Serag El-Dien et al., 2017).