RT-qPCR results confirmed that ANGPT2 (Figure 7A), HSP90AA1 (Figure 7B), PDE1C (Figure 7C), APOD (Figure 7D), and HSPA1A (Figure 7E) mRNAs were markedly upregulated in blood specimens from PD patients compared with healthy participants. This evidence concerns the gene ANGPT2 and Parkinson disease.