The cytokine profile of patients with COVID-19 and sHLH was similar with elevated serum levels of IL1, IL2, IL4, IL6, IL7, IL8, IL10, IL-18, TNFα, GCSF, IP-10, MCP1, MIP1α, CXCL9, CXCL-10, IFN-γ (63–66). This evidence concerns the gene IL1B and COVID-19.