As in many invasive infection processes initiated within the GIT, the pathogen is expected to develop strategies aimed at destroying the adherens junctions insured by cell adhesion molecules (CAM), such as E-cadherin (E-Cad), to create epithelium micro-damage, to dysregulate the immune response, and/or to invade the host (Devaux et al., 2019). Here, CDH1 is linked to infection.