As shown in Figures 5H,I, p-Stat3 and p-Jak2 were induced by overexpression of miR-877-3p, and suppressed by knockdown of miR-877-3p in both SGC7901 and BGC823 cells, which was further validated by western blot analysis on the tumor samples derived from the mouse model (Figure 5J). The gene discussed is STAT3; the disease is neoplasm.