SYK and asthma: Compared with those in the asthma model groups, similar to the activation of Syk, the phosphorylation levels of MAPKs and GR-Ser226 after Dex and R406 treatment were mitigated, which revealed that Syk may regulate the phosphorylation level of GR-Ser226 by mediating the activation of MAPKs, thus affecting sensitivity to dexamethasone.