For instance, ANLN is a well-known oncogene that promotes carcinogenesis and therapeutic resistance in multiple types of cancers, such as LUAD (Long et al., 2018; Xu et al., 2019; Deng et al., 2021), oral cancer (Wang B et al., 2021), colorectal cancer (Liu et al., 2022), breast cancer (Wang et al., 2020; Maryam and Chin, 2021), pancreatic cancer (Wang et al., 2019), and head and neck squamous cell carcinoma (Guo et al., 2021). The gene discussed is ANLN; the disease is lip and oral cavity carcinoma.