PROX1 and retinal disorder: These analyses showed effects of retinopathy-associated genotypes on increased gene expression for PCSK9 (rs2479409) in skin fibroblasts, for CYP2C19*2 (rs4244285) in skin fibroblasts, liver, and stomach, and for PROX1 (rs340874) in the brain (Supplementary Table 7; Consortium, 2015).