KDR and thyroid gland carcinoma: Some antiangiogenic MKIs (e.g., pazopanib, sunitinib, anlotinib, axitinib, and dovitinib) are effective for the treatment of thyroid cancer, mainly through the inhibition of VEGFR, fibroblast growth factor 1/2, platelet-derived growth factor receptor, and RET receptors (126).