The factors identified [disease and treatment coherence, emotional burden, self-administration, and treatment-related anxiety] correspond with the wider literature, which has identified factors associated with non-adherence to r-hGH treatment (5, 9, 14, 28–30) and in addition explored the views, perceptions, and experiences of parents/caregivers of children receiving r-hGH treatment (31–33). Here, GH1 is linked to Anxiety.