The OR calculations clearly supported the results of Pearson’s correlation, indicating the higher risk of the development of T1D in populations consuming tetracycline (J01A) and narrow-spectrum penicillin (J01CE, J01CF), while broad-spectrum antibiotics [broad-spectrum, beta-lactamase-resistant combination penicillin (J01CR), cephalosporin (J01D), macrolides (J01F), and quinolone (J01M)] exhibited inhibitory effects on the development of T1D. Here, LACTB is linked to type 1 diabetes mellitus.