Before NPs values were included in the adjusted model, the association of anemia with increased mortality remained statistically significant (HR: 1.20, 95% CI:1.03–1.40, p = 0.020) after adjustment for age, sex, BMI, systolic blood pressure, current smoker, diabetes, COPD, coronary heart disease, decreased eGFR, hyponatremia, in-hospital left ventricular ejection fraction, NYHA class and hospital levels, and the use of renin-angiotensin system inhibitors, β-blockers, mineralocorticoid receptor antagonists and statin at discharge. The gene discussed is NR3C2; the disease is chronic obstructive pulmonary disease.