Furthermore, compared with the expression profiles of cancer histological subtypes, there was a statistically significant difference in SOCS3 expression among BLCA, LUAD, THYM, UCEC, LIHC, MESO, TGCT, and THCA subtypes, and SOCS3 expression was higher in all histological subtypes compared with the corresponding normal adjacent tissues in BLCA, LUAD, THYM, and THCA (Figure 4; Table 1). Here, SOCS3 is linked to bladder transitional cell carcinoma.