Additionally, patients with luminal A subtype are more likely to have bone metastases (luminal A: 48.10%, luminal B: 32.74%, HER2-positive: 16.60%, triple negative: 21.18%), whereas HER2-positive and triple negative BC had a higher proportion of viscera metastasis (luminal A: 51.90%, luminal B: 67.26%, HER2-positive: 83.23%, triple negative: 78.82%), which were consistent with previous studies (28–30). This evidence concerns the gene ERBB2 and breast cancer.