CD4 and neoplasm: TIMER analysis of the mechanisms underlying CRIM1 effects on breast cancer revealed that CRIM1 levels were negatively linked to tumor purity, macrophage M1, Tregs, NK cells, B-cells, and CD4+ T-cells, but were positively correlated with CD8+ T-cells, endothelial cells, macrophage M1 as well as neutrophils.