Overexpression of PINK1 in the PINK1-/-plus huPINK1 population increased tumor growth by day 19 compared to PINK1-/- RasG12D-transformed cells (Figure 1G), although the rescue effect was less pronounced than in soft agar (mean tumor volume on day 19: WT = 1413 mm3; PINK1-/-= 700 mm3; PINK1-/-plus huPINK1 = 911 mm3). The gene discussed is PINK1; the disease is neoplasm.