These databases indicated that COPB2 was closely associated with PCa, and further clinical data were needed to verify the clinical relevance of COPB2. According to the samples and information collected from 118 patients with PCa who underwent radical prostatectomy (RP), the correlation between COPB2 expression level, clinical characteristics, and biochemical recurrence of PCa were analyzed. The gene discussed is COPB2; the disease is posterior cortical atrophy.