In the context of oral cancer, a recent study by Ohshima et al. found Streptococcus gordonii (a health-associated oral bacteria) to antagonize the expression of pro-cancer molecule/ZEB2 induced by Porphyromonas gingivalis in oral epithelial cells [12], suggesting it may have a protective role against oral cancer. Here, ZEB2 is linked to lip and oral cavity carcinoma.