Mutations in CACNA1A gene have been demonstrated to be associated with a wide range of paroxysmal diseases, such as episodic ataxia type 2 (EA2; MIM: 108500), familial hemiplegic migraine 1 (FHM1; MIM: 141500), spinocerebellar ataxia 6 (SCA6; MIM: 183086), and developmental epileptic encephalopathy 42 (DEE42; MIM: 617106). This evidence concerns the gene CACNA1A and spinocerebellar ataxia type 6.