The results showed that elevated MCV and ALP, acute renal failure, and medication of digoxin could increase the risk of death in ICU-admitted patients with hypertensive chronic kidney disease, while elevated ALB and MCHC, history of renal surgery, concomitance of hyperlipemia, and history of coronary angiogram could decrease the risk of death in the patients. This evidence concerns the gene ALB and hypertensive nephropathy.